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PPDO滑扣型血管支架制备方法与性能研究

李瑜 卞平艳 童景琳

李瑜, 卞平艳, 童景琳. PPDO滑扣型血管支架制备方法与性能研究[J]. 机械科学与技术, 2015, 34(10): 1604-1608. doi: 10.13433/j.cnki.1003-8728.2015.1024
引用本文: 李瑜, 卞平艳, 童景琳. PPDO滑扣型血管支架制备方法与性能研究[J]. 机械科学与技术, 2015, 34(10): 1604-1608. doi: 10.13433/j.cnki.1003-8728.2015.1024
Li Yu, Bian Pingyan, Tong Jinglin. Investigation of Preparations and Characters of PPDO Slide Fastener Type Stents[J]. Mechanical Science and Technology for Aerospace Engineering, 2015, 34(10): 1604-1608. doi: 10.13433/j.cnki.1003-8728.2015.1024
Citation: Li Yu, Bian Pingyan, Tong Jinglin. Investigation of Preparations and Characters of PPDO Slide Fastener Type Stents[J]. Mechanical Science and Technology for Aerospace Engineering, 2015, 34(10): 1604-1608. doi: 10.13433/j.cnki.1003-8728.2015.1024

PPDO滑扣型血管支架制备方法与性能研究

doi: 10.13433/j.cnki.1003-8728.2015.1024
基金项目: 

国家自然科学基金项目(81070134)与河南省高校精密制造技术与工程重点学科开放实验室基金项目(PMTE201305A)资助

详细信息
    作者简介:

    李瑜(1982-),实验师,硕士,研究方向为生物制造与增材制造,精密超精密制造,liyu@hpu.edu.cn

Investigation of Preparations and Characters of PPDO Slide Fastener Type Stents

  • 摘要: 比较成形工艺对聚对二氧环已酮(PPDO)滑扣式可降解血管支架性能的影响。对微压印和3D打印(3DP)两种聚合物成形工艺进行比较,主要包括其成形表面质量和径向强度两方面。试验结果显示:微压印制备支架内表面Ra0.429、外表面Ra1.24,优于3DP制备支架,而支架内外表面质量的差异化与可控性也更适合血管支架在抑制凝血和置放稳定等临床医学的需要;另外,两种制备方法所制支架的径向强度均高于临床需要的80 kPa的标准,其中微压印比3DP略高4%。原因可能是微压印制备将PPDO材料的成形温度降低在材料粘流态温度范围内,使该高分子材料的热降解大大降低,较好的保留了原材料的力学性能与强度保障时间。
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出版历程
  • 收稿日期:  2013-11-08
  • 刊出日期:  2015-10-05

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